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Job Name
Enter a simple name to identify your Antifold design job. Example: antifold_design1
Upload PDB File
Upload a 3D protein structure file in .pdb format. The structure will be used as the input for sequence design.
Drag & Drop or Click to Browse (Supported: .pdb)
Select Input Type
Choose whether you would like to use HeavyChain or NanoBody.
Use HeavyChain
Use Nanobody
Heavy Chain
Specify the chain ID for the heavy chain (e.g., 'A'). Used mainly for antibody design.
Light Chain
Specify the chain ID for the light chain if applicable. Leave blank if not needed. Example: 'B'
Antigen Chain
Enter the chain ID for the antigen (e.g., 'C') if designing an antibody-antigen complex.
Number of Sequences per Target
Set how many designed sequences you want to generate per structure. Example: 10.
Sampling Temperature
Controls sequence diversity: lower values (e.g., 0.2) generate more conservative designs, higher values create more diverse options.
Regions
Select which antibody loop regions to redesign (e.g., 'CDR-H1 CDR-H3'); default targets main CDR loops.
ESM-IF1 Evaluation Mode
Enable (TRUE) or disable (FALSE) evaluation of designed sequences using the ESM-IF1 inverse folding model.
TRUE
FALSE
Run Analysis
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